Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 34 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (elemental) (from 20 mg L-Selenomethionine)
100 mcg
182%
Top Medical Research Studies
9
We investigated how selenium supplementation affects cholesterol levels and the associated molecular changes. Using Sprague-Dawley male rats, we fed them diets supplemented with selenium alongside high cholesterol for three months.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
Read More
9
Selenium nanoparticles show limited effectiveness
We investigated whether selenium nanoparticles (SeNPs) could combat atherosclerosis related to high cholesterol. In our study involving apolipoprotein E deficient mice on a high-fat diet, both BSA- and chitosan-coated SeNPs showed promise in reducing atherosclerotic lesions over 12 weeks.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
Read More
9
We explored the effects of selenium nanoparticles on high cholesterol by studying ApoE-deficient mice on a high-fat diet. Over eight weeks, we noted that selenium nanoparticles significantly reduced total cholesterol and triglycerides while boosting beneficial HDL levels.
Additionally, these nanoparticles improved vascular health and regulated important genes for cholesterol metabolism while enhancing antioxidant enzyme activities. However, it's important to note that while the results were promising in mice, the findings do not directly translate to humans yet.
Additionally, these nanoparticles improved vascular health and regulated important genes for cholesterol metabolism while enhancing antioxidant enzyme activities. However, it's important to note that while the results were promising in mice, the findings do not directly translate to humans yet.
Read More
Most Useful Reviews
9
Reduces bad cholesterol
222 people found this helpful
I started taking this microelement recently, and it's incredibly beneficial. It thins the blood and reduces bad cholesterol levels. Alongside its anti-inflammatory properties, it supports my nervous system and weight control. I take selenium with zinc and quercetin, and this healthy combination has proven effective for both me and my husband.
Read More
9
High quality recommendation
107 people found this helpful
I take selenium along with iodine courses and find them quite effective. My condition has greatly improved, and I highly recommend this high-quality and affordable brand.
Read More
9
Cardiovascular benefits
80 people found this helpful
Selenium is vital for the heart, immunity, and thyroid health. It helps remove heavy metals, lowers bad cholesterol, and mitigates oxidative stress, thereby protecting against conditions such as atherosclerosis and heart disease. A highly recommended supplement for overall health!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
- All Researches
9
Selenium nanoparticles show limited effectiveness
We investigated whether selenium nanoparticles (SeNPs) could combat atherosclerosis related to high cholesterol. In our study involving apolipoprotein E deficient mice on a high-fat diet, both BSA- and chitosan-coated SeNPs showed promise in reducing atherosclerotic lesions over 12 weeks.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
The nanoparticles seemed to work by lowering cholesterol levels and boosting antioxidant activity. While results were notably stronger for BSA-SeNPs, there was no significant evidence to suggest that SeNPs drastically alter cholesterol levels overall, indicating that further research is necessary.
Read More
9
We explored the effects of selenium nanoparticles on high cholesterol by studying ApoE-deficient mice on a high-fat diet. Over eight weeks, we noted that selenium nanoparticles significantly reduced total cholesterol and triglycerides while boosting beneficial HDL levels.
Additionally, these nanoparticles improved vascular health and regulated important genes for cholesterol metabolism while enhancing antioxidant enzyme activities. However, it's important to note that while the results were promising in mice, the findings do not directly translate to humans yet.
Additionally, these nanoparticles improved vascular health and regulated important genes for cholesterol metabolism while enhancing antioxidant enzyme activities. However, it's important to note that while the results were promising in mice, the findings do not directly translate to humans yet.
Read More
9
Selenium may help cholesterol levels
We investigated the effects of selenium supplementation on LDL receptor activity and mRNA expression in male rats with high cholesterol. The study involved feeding the rats diets with varying selenium levels along with a high-cholesterol diet over three months.
Our results showed that while high cholesterol reduced both LDL receptor activity and mRNA expression, selenium at 1 ppm effectively improved these measures. This suggests that selenium may play a positive role in managing cholesterol levels and supporting lipid metabolism.
Our results showed that while high cholesterol reduced both LDL receptor activity and mRNA expression, selenium at 1 ppm effectively improved these measures. This suggests that selenium may play a positive role in managing cholesterol levels and supporting lipid metabolism.
Read More
9
We investigated how selenium supplementation affects cholesterol levels and the associated molecular changes. Using Sprague-Dawley male rats, we fed them diets supplemented with selenium alongside high cholesterol for three months.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.
Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.
Read More
9
We explored how selenium affects lipid levels in rats consuming a high-cholesterol diet over ten weeks. By comparing selenium-treated groups with control rats, we found that selenium effectively reduced triglycerides, total cholesterol, and low-density lipoprotein cholesterol.
Additionally, it inhibited liver fat accumulation. These findings suggest that selenium could play a beneficial, recuperative role against high cholesterol. However, it's important to note that this research is based on animal studies, so human applicability requires further investigation.
Additionally, it inhibited liver fat accumulation. These findings suggest that selenium could play a beneficial, recuperative role against high cholesterol. However, it's important to note that this research is based on animal studies, so human applicability requires further investigation.
Read More
User Reviews
USERS' SCORE
Good
Based on 34 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduces bad cholesterol
222 people found this helpful
I started taking this microelement recently, and it's incredibly beneficial. It thins the blood and reduces bad cholesterol levels. Alongside its anti-inflammatory properties, it supports my nervous system and weight control. I take selenium with zinc and quercetin, and this healthy combination has proven effective for both me and my husband.
Read More
9
High quality recommendation
107 people found this helpful
I take selenium along with iodine courses and find them quite effective. My condition has greatly improved, and I highly recommend this high-quality and affordable brand.
Read More
9
Cardiovascular benefits
80 people found this helpful
Selenium is vital for the heart, immunity, and thyroid health. It helps remove heavy metals, lowers bad cholesterol, and mitigates oxidative stress, thereby protecting against conditions such as atherosclerosis and heart disease. A highly recommended supplement for overall health!
Read More
9
Boosts reproductive health
53 people found this helpful
This organic selenium is fantastic! At a consumption level of 70-150 mcg, it protects against cancer and decelerates aging. Since starting, my health issues have subsided, and my nails are growing rapidly. It's also beneficial for male reproductive health—definitely recommend it!
Read More
7.5
Supports cholesterol levels
9 people found this helpful
Selenium is a crucial microelement that supports numerous bodily functions, including hormone and enzyme production, and combats aging. It plays a significant role in cardiovascular health, aiding in fat metabolism and maintaining cholesterol levels. Additionally, selenium protects blood vessels and the heart muscle, reducing hypertension risk. I'm satisfied with the quality and highly recommend it!
Read More
Frequently Asked Questions
9
Reduced symptoms
1 people found this helpful
I take selenium (selenomethionine) for thyroid management due to high autoimmune markers and symptoms. After a week, my irritability and fatigue lessened, and after two months, my antibody levels normalized. I plan to continue with it.
9
Replenishes deficiency quickly
Excellent quality with well-selected ingredients. The capsules are appropriately sized and easy to swallow. The evident benefits include fast replenishment of deficiencies. Almost immediately, I noticed symptom alleviation. The taste is acceptable, and I am completely satisfied. I wholeheartedly recommend this product to everyone.
7.5
Comprehensive support
4 people found this helpful
I take Selenium 100 as prescribed by my doctor due to my high cholesterol and plaques in my blood vessels. It strengthens blood vessels and reduces the risk of cholesterol plaque formation. The tablets are easy to swallow and the packaging is compact for travel. I've had reliable results with this brand, and it arrived promptly.
7.5
Improves cardiovascular health
5 people found this helpful
I take selenium for cardiovascular issues, including the prevention of hypertension and to help restore heart function post-myocardial infarction. It normalises blood cholesterol, supports flexibility in blood vessels, and aids recovery from injuries. The quality of this supplement is consistently excellent.
7.5
Fat loss benefits
240 people found this helpful
Reduces the level of bad cholesterol, has anti-inflammatory properties, and helps control weight. I take Selenium along with Zinc, which aids the body in eliminating heavy metals.
9
Reduces bad cholesterol
222 people found this helpful
I started taking this microelement recently, and it's incredibly beneficial. It thins the blood and reduces bad cholesterol levels. Alongside its anti-inflammatory properties, it supports my nervous system and weight control. I take selenium with zinc and quercetin, and this healthy combination has proven effective for both me and my husband.
9
Thyroid health
1 people found this helpful
I highly recommend Selenium, which I started on my endocrinologist's advice. It significantly improved my hormonal balance and the "lump" in my throat disappeared. Overall, my health has greatly improved.
9
Aging benefits noted
1 people found this helpful
I have been using selenium for three years, enjoying its numerous benefits for beauty and health. It helps maintain youthful skin, hair, and nails, while also supporting thyroid function. I recommend this, particularly in conjunction with iodine and vitamin E for optimal effects.
7.5
Mood improvement
2 people found this helpful
I really liked the Selenium dietary supplement. The ingredient quality is high, and I find the packaging convenient. I take one tablet daily, and I've noticed improvements in my mood and energy levels. I also had tests for thyroid hormones recently, and everything came back normal. I definitely recommend it!
9
High quality recommendation
107 people found this helpful
I take selenium along with iodine courses and find them quite effective. My condition has greatly improved, and I highly recommend this high-quality and affordable brand.
9
Excellent for thyroid
2 people found this helpful
Recommended by a friend, Super Selenium Tonic is gluten-free and fits well with my ketogenic diet. I've been taking one pill daily for two weeks and have combined it with other supplements like magnesium and potassium citrate. I feel less fatigued; I recommend this to anyone looking for thyroid support.
7.5
Blood thinner effects
3 people found this helpful
This microelement thins the blood, preventing clots and lowering bad cholesterol levels. It effectively reduces the risk of atherosclerosis and supports the nervous system with anti-inflammatory properties. I consistently take this selenium supplement, and it's perfect for the entire family.
9
Effective thyroid control
1 people found this helpful
I've experienced excellent results in reducing my TSH levels, going from 4.95 to 1.3 after combining selenium with iodine. I advise taking smaller doses to avoid skin irritation as excessive selenium can cause side effects. The drug is indeed effective!
References
- Zhang R, Xie X, Liu J, Pan R, Huang Y, et al. A novel selenoglycoside compound GlcSeCys alleviates diets-induced obesity and metabolic dysfunctions with the modulation of Galectin-1 and selenoproteins. Life Sci. 2024;359:123259. 10.1016/j.lfs.2024.123259
- Xiao S, Mao L, Xiao J, Wu Y, Liu H. Selenium nanoparticles inhibit the formation of atherosclerosis in apolipoprotein E deficient mice by alleviating hyperlipidemia and oxidative stress. Eur J Pharmacol. 2021;902:174120. 10.1016/j.ejphar.2021.174120
- Fang H, He X, Wu Y, Chen S, Zhang M, et al. Association Between Selenium Level in Blood and Glycolipid Metabolism in Residents of Enshi Prefecture, China. Biol Trace Elem Res. 2021;199:2456. 10.1007/s12011-020-02372-9
- Guo L, Xiao J, Liu H, Liu H. Selenium nanoparticles alleviate hyperlipidemia and vascular injury in ApoE-deficient mice by regulating cholesterol metabolism and reducing oxidative stress. Metallomics. 2020;12:204. 10.1039/c9mt00215d
- Carvalho RF, Huguenin GV, Luiz RR, Moreira AS, Oliveira GM, et al. Intake of partially defatted Brazil nut flour reduces serum cholesterol in hypercholesterolemic patients--a randomized controlled trial. Nutr J. 2015;14:59. 10.1186/s12937-015-0036-x
- Harisa GI, Abo-Salem OM, El-sayed el-SM, Shazly G. Effects of nutritional and excessive levels of selenium on red blood cells of rats fed a high cholesterol diet. Biol Trace Elem Res. 2013;152:41. 10.1007/s12011-012-9588-1
- Kaur H, Bansal MP. Studies on scavenger receptors under experimental hypercholesterolemia: modulation on selenium supplementation. Biol Trace Elem Res. 2011;143:310. 10.1007/s12011-010-8833-8
- Poirier J, Cockell KA, Ratnayake WM, Scoggan KA, Hidiroglou N, et al. Antioxidant Supplements Improve Profiles of Hepatic Oxysterols and Plasma Lipids in Butter-fed Hamsters. Nutr Metab Insights. 2010;3:1. 10.4137/NMI.S3911
- Kaur HD, Bansal MP. Studies on HDL associated enzymes under experimental hypercholesterolemia: possible modulation on selenium supplementation. Lipids Health Dis. 2009;8:55. 10.1186/1476-511X-8-55
- Agbor GA, Vinson JA, Patel S, Patel K, Scarpati J, et al. Effect of selenium- and glutathione-enriched yeast supplementation on a combined atherosclerosis and diabetes hamster model. J Agric Food Chem. 2007;55:8731.
- Dhingra S, Bansal MP. Hypercholesterolemia and LDL receptor mRNA expression: modulation by selenium supplementation. Biometals. 2006;19:493.
- Dhingra S, Bansal MP. Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation. Chem Biol Interact. 2006;161:49.
- Dhingra S, Bansal MP. Hypercholesterolemia and apolipoprotein B expression: regulation by selenium status. Lipids Health Dis. 2005;4:28.
- Leborgne L, Pakala R, Dilcher C, Hellinga D, Seabron R, et al. Effect of antioxidants on atherosclerotic plaque formation in balloon-denuded and irradiated hypercholesterolemic rabbits. J Cardiovasc Pharmacol. 2005;46:540.
- Sato J, O'Brien T, Katusic ZS, Fu A, Nygren J, et al. Dietary antioxidants preserve endothelium dependent vasorelaxation in overfed rats. Atherosclerosis. 2002;161:327.
- Iizuka Y, Sakurai E, Tanaka Y. [Effect of selenium on serum, hepatic and lipoprotein lipids concentration in rats fed on a high-cholesterol diet]. Yakugaku Zasshi. 2001;121:93.
